Agenda
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Friday, September 9
Thursday, September 8, 2022
7:00 – 8:00 am | Registration & Refreshments LOBBY & BALLROOM A, FIRST FLOOR |
MAIN MEETING SESSION: BALLROOM B, SECOND FLOOR |
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8:10 – 8:10 am | Welcome and Opening Remarks Alison Morris, MD, MS; University of Pittsburgh Janet Lee, MD; University of Pittsburgh Tomeka Suber, MD, PhD; University of Pittsburgh |
Session 1: | THE STATE OF METABOLISM RESEARCH IN HEALTH SCIENCES: METABOLISM, BIOENERGETICS, AND THE TOOLS OF THE TRADE |
Session Chairs: | Janet S. Lee, MD; University of Pittsburgh Anuradha Ray, PhD; University of Pittsburgh Nathaniel Weathington, MD, PhD; UPMC |
8:10 – 8:20 am | Session Chair Introduction |
8:20 – 8:40 am | Aging, Metabolism and Autophagy Toren Finkel, MD, PhD University of Pittsburgh |
8:40 - 8:45 am | Q & A |
8:45 – 9:05 am | Overview of Metabolomics Analysis Stacy Gelhaus Wendell, PhD University of Pittsburgh |
9:05 - 9:10 am | Q & A |
9:10 – 9:30 am | Cellular Measurements and Metabolism William M. Oldham, MD, PhD Harvard Medical School |
9:30 – 9:35 am | Q & A |
9:35 - 9:55 am | Refreshment Break BALLROOM A, FIRST FLOOR |
MAIN MEETING SESSION: BALLROOM B, SECOND FLOOR |
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Session 2: | ALTERATIONS TO METABOLISM AS A DRIVER OF PULMONARY VASCULAR DISEASE |
Session Chairs: | Brett Kaufman, PhD; University of Pittsburgh Lianghui Zhang, MD, PhD; University of Pittsburgh |
9:55 - 10:00 am | Session Chair Introduction |
10:00 – 10:20 am | Alterations to Metabolism as a driver of Pulmonary Vascular Disease Sruti Shiva, PhD University of Pittsburgh |
10:20 - 10:25 am | Q & A |
10:25 – 10:45 am | Noncoding RNAs Direct Metabolism in Pulmonary Hypertension Physiology Stephen Y. Chan, MD, PhD, FAHA University of Pittsburgh |
10:45 - 10:50 am | Q & A |
10:50 - 11:05 am | Refreshment Break BALLROOM A, FIRST FLOOR |
MAIN MEETING SESSION: BALLROOM B, SECOND FLOOR |
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Rapid Fire #1: | EARLY CAREER ORAL PRESENTATIONS |
Moderators: | Fernando Holguin, MD; University of Colorado, Denver Tomeka Suber, MD, PhD; University of Pittsburgh |
11:05 – 11:10 am | Introductions |
11:10 – 11:20 am | Abstract Oral Presentation #1: Lung Cell Profiling in Multiomic Mesenchymal Cell Profiling in Systemic Sclerosis-associated Interstitial Lung Disease Eleanor B. Valenzi, MD University of Pittsburgh |
11:20 – 11:25 am | Q & A |
11:25 – 11:35 am | Abstract Oral Presentation #2: Pulmonary Vascular Disease in COPD Aparna Balasubramanian, MD, MHS Johns Hopkins University School of Medicine |
11:35 – 11:40 am | Q & A |
11:40 – 11:50 am | Abstract Oral Presentation #3: Airway Immune Pathways in Allergic Asthma Jehan W. Alladina, MD Massachusetts General Hospital, Harvard Medical School |
11:50 – 11:55 am | Q & A |
12:00 – 12:45 pm | Lunch (provided) GOLD ROOM, SECOND FLOOR |
12:45 – 2:00 pm | Poster Session and Refreshments BALLROOM A, FIRST FLOOR |
MAIN MEETING SESSION: BALLROOM B, SECOND FLOOR |
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Session 3: | STUDYING AIRWAYS DISEASE THROUGH THE LENS OF METABOLISM |
Session Chairs: | Oliver Eickelberg, MD; University of Pittsburgh Frank C. Sciurba, MD, FCCP; University of Pittsburgh |
2:00 – 2:10 pm | Session Chair Introduction |
2:10 – 2:30 pm | Immunometabolism Changes in COPD Patients Suzanne Cloonan, PhD Trinity College, Dublin |
2:30 - 2:35 pm | Q & A |
2:35 - 2:55 pm | The Interplay of Metabolism and Regenerative Signaling Pathways in Chronic Lung Disease Melanie Königshoff, MD, PhD University of Pittsburgh |
2:55 - 3:00 pm | Q & A |
3:00 - 3:20 pm | Airway Neutrophil Metabolism Impacts Cystic Fibrosis Bacterial Colonization Prof. Gerry McElvaney Royal College of Surgeons in Ireland |
3:20 - 3:25 pm | Q & A |
3:25 - 3:45 pm | Refreshment Break BALLROOM A, FIRST FLOOR |
MAIN MEETING SESSION: BALLROOM B, SECOND FLOOR |
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Session 4: | UNLOCKING THE ROLE OF METABOLISM AND MITOCHONDRIA IN LUNG PARENCHYMAL DISEASE AND CANCER |
Session Chairs: | Mauricio Rojas, MD; Ohio State University Nadia Hansel, MD; Johns Hopkins School of Medicine |
3:45 – 3:50 pm | Session Chair Introduction |
3:50 – 4:10 pm | Mitochondrial Changes in Idiopathic Pulmonary Fibrosis Ana Mora, MD Ohio State University |
4:10 – 4:15 pm | Q & A |
4:15 – 4:35 pm | Diverse Metabolic Signaling in Myeloid Cells as a Driver of Fibrotic Lung Disease G.R. Scott Budinger, MD Northwestern Feinberg School of Medicine |
4:35 – 4:40 pm | Q & A |
4:40 – 5:00 pm | Tumor Immunity and Metabolism in Cancer Tullia C. Bruno, PhD University of Pittsburgh |
5:00 – 5:05 pm | Q & A |
5:05 – 5:25 pm | Mitochondria of Alveolar Type 2 Cells Determine Severity of the Lung’s Innate Immunity M. Naeem Islam, PhD Columbia University |
5:25 – 5:30 pm | Q & A |
5:45 pm | Adjournment |
5:45 – 6:15 pm | Travel Time to Reception |
6:00 – 9:00 pm | Reception CARNEGIE SCIENCE CENTER (please wear your name badge for admittance) "Do you believe in miracles? Yes, at the Monongahela River!" Special guest speaker: Augustine M.K. Choi, MD; Stephen and Suzanne Weiss Dean, Weill Cornell Medicine Provost for Medical Affairs, Cornell University |
9:00 pm | Return Transportation to Hotels |
Friday, September 9, 2022
7:30 – 8:00 am | Registration and Refreshments LOBBY & BALLROOM A, FIRST FLOOR |
MAIN MEETING SESSION: BALLROOM B, SECOND FLOOR |
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Session 5: | METABOLISM AS A DRIVER OF IMMUNE RESPONSES AND IN PULMONARY TRANSPLANT |
Session Chairs: | Chadi Hage, MD; University of Pittsburgh Mark Snyder, MD; University of Pittsburgh |
8:00 – 8:15 am | Welcome and Session Chair Introduction |
8:15 – 8:35 am | Mitochondrial ROS Fine-tunes Lung Dendritic Cells to Regulate Allergic Disease Anuradha Ray, PhD University of Pittsburgh |
8:35 – 8:40 am | Q & A |
8:40 – 9:00 am | Immunometabolism as a Determinant in Success or Failure of Bone Marrow Transplant Craig A. Byersdorfer, MD, PhD University of Pittsburgh |
9:00 – 9:05 am | Q & A |
9:05 – 9:20 am | Refreshment Break BALLROOM A, FIRST FLOOR |
MAIN MEETING SESSION: BALLROOM B, SECOND FLOOR |
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Session 6: | MODULATIONS OF METABOLISM IN IMMUNITY AND INFECTION |
Session Chairs: | Barbara Methé, PhD; University of Pittsburgh Prabir Ray, PhD; University of Pittsburgh |
9:20 – 9:25 am | Session Chair Introduction |
9:25 – 9:45 am | Persistence of Klebsiella and Pseudomonas in the Respiratory Tract by Metabolite Adaptation and Implications in Pathogenicity Alice Prince, MD Columbia University |
9:45 – 9:50 am | Q & A |
9:50 – 10:10 am | Metabolic Determinants in the Pathogenesis of Legionella Infection Sunny Shin, PhD University of Pennsylvania |
10:10 – 10:15 am | Q & A |
10:15 – 10:35 am | Pseudomonas Microbial Metabolism and Adaptation in the CF Microenvironment Jennifer M. Bomberger, PhD Geisel School of Medicine at Dartmouth |
10:35 – 10:40 am | Q & A |
10:40 – 11:00 AM | Refreshment Break BALLROOM A, FIRST FLOOR |
MAIN MEETING SESSION: BALLROOM B, SECOND FLOOR |
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Rapid Fire #2 | EARLY CAREER ORAL PRESENTATIONS |
Moderator: | Jessica Bon, MD, MS; University of Pittsburgh Anna Zemke, MD, PhD; University of Pittsburgh |
11:00 – 11:05 am | Introductions |
11:05 – 11:15 am | Abstract Oral Presentation #4: Immune Pathways in Severe Asthma Marc C. Gauthier, MD University of Pittsburgh |
11:15 – 11:20 am | Q & A |
11:20 – 11:30 am | Abstract Oral Presentation #5: Metabolism in the Lung Microbiome after Lung Transplantation John E. McGinniss, MD University of Pennsylvania |
11:30 – 11:35 am | Q & A |
11:35 – 11:45 am | Abstract Oral Presentation #6: Maresin 1/LGR6 axis in the resolution of Respiratory Syncytial Virus- induced inflammation Nandini Krishnamoorthy, PhD Harvard Medical School, Brigham & Women’s Hospital |
11:45 – 11:50 am | Q & A |
11:50 am – 1:00 pm | Lunch (provided) GOLD ROOM, SECOND FLOOR |
MAIN MEETING SESSION: BALLROOM B, SECOND FLOOR |
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1:00 – 2:00 pm | Panel Discussion |
CHANGING PATTERNS OF PUBLICATIONS AND ITS IMPACT ON ACADEMIC SUCCESS
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2:00 – 2:15 pm | Refreshment Break BALLROOM A, FIRST FLOOR |
MAIN MEETING SESSION: BALLROOM B, SECOND FLOOR |
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Session 7: | METABOLIC AND PHYSIOLOGIC DETERMINANTS OF COVID PATHOGENESIS |
Session Chairs: | Georgios Kitsios, MD, PhD; University of Pittsburgh John McDyer, MD; University of Pittsburgh |
2:15 – 2:20 pm | Session Chair Introduction |
2:20 – 2:40 pm | Immuno-metabolomes and Immuno-lipidomes in COVID-19 Charles Dela Cruz, MD, PhD Yale University |
2:40 – 2:45 pm | Q & A |
2:45 – 3:05 pm | Metabolic Vulnerabilities in COVID-19 Peter Mullen, PhD USC Keck School of Medicine |
3:05 – 3:10 pm | Q & A |
3:10 – 3:35 pm | Refreshment Break BALLROOM A, FIRST FLOOR |
MAIN MEETING SESSION: BALLROOM B, SECOND FLOOR |
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Session 8: | TARGETING METABOLISM FOR NOVEL THERAPIES |
Session Chairs: | Faraaz Shah, MD, MPH; University of Pittsburgh Alison Morris, MD, MS; University of Pittsburgh |
3:35 – 3:40 pm | Session Chair Introduction |
3:40 – 4:00 pm | Understanding Metabolic Changes in Patients with Sepsis Matthew Rosengart, MD, MPH University of Pittsburgh |
4:00 – 4:05 pm | Q & A |
4:05 – 4:25 pm | The Interplay of Metabolism and Sleep Physiology Vsevolod Y. Polotsky, MD, PhD Johns Hopkins University |
4:25 – 4:30 pm | Q & A |
4:30 – 4:45 pm | Poster Recognitions |
4:45 – 5:00 pm | Concluding Remarks Alison Morris, MD, MS |
5:00 pm | Adjournment |